Loss of compression in two cylinders

2006 DODGE TRUCK
250,000 MILES
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LAURA SANDERS
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Loss of compression in two cylinders and no compression when you accelerate while driving. What would cause first two cylinders to have lower compression than other six cylinder?
Jul 30, 2017 at 9:35 AM
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DOCFIXIT
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If the cylinders are side by side most likely a blown head gasket.
Jul 30, 2017 at 2:10 PM